Fick principle

English Etymology en Adolf Eugen Fick German physician and physiologist 1829 1901. Proper noun en physiology A principle used in physiology and medicine, originally applied to measure cardiac output, stating that the total uptake (or release) of a substance by an organ is equal to the product of the blood flow through the organ and the arteriovenous concentration difference of the substance. en 1951 March J. H. Lehmann; A. D. Johnson; W. C. Bridges; J. Michel; D. M. Green Cardiac Catheterization—A Diagnostic Aid in Congenital Heart Disease Northwest Medicine 50 3 Portland, Ore. Northwest Medical Publishing Association 171 https://archive.org/details/northwestmedicin5019nort/page/170/mode/2up?q=%22Fick+principle%22 The rate of blood flow in the peripheral and pulmonic vessels and the approximate size of existing shunts can be calculated by application of the Fick principle. It may be of interest to explain in some detail the Fick principle as employed in calculation of cardiac output, pulmonic blood flow and blood flow in shunts.