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Alexander disease

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English Alternative forms en Alexander's disease Etymology Named after the American physician Dr. W. Stewart Alexander, who was the first to describe the disorder in 1949. Noun - A rare, progressive, and usually fatal neurological disorder; classified as a leukodystrophy, it is fundamentally a disease of the brain’s astrocytes; caused by genetic mutations that lead to the abnormal accumulation of proteins, known as Rosenthal fibers, which destroy the protective myelin sheath in the central nervous system. Further reading en eponyms en Diseases