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411 REFERENCE · Wiktionary

Philadelphia chromosome

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English thumb|The translocation Etymology The abnormality was first discovered and described in 1959 by David Hungerford from the Fox Chase Cancer Center Institute for Cancer Research and Peter Nowell from the University of Pennsylvania School of Medicine. Both facilities are located in Philadelphia, Pennsylvania. Noun Human chromosome 22, after it has, pathologically, traded some of its genetic material with chromosome 9; this often causes chronic myelogenous leukemia. en Ph chromosome Further reading