Bioinformatics

Contents Foreword Introduction Part One: Molecular Biology /The central dogma of molecular biology/ /DNA structure/ /RNA structure/ /Protein & Nucleic acid/ /Human Genome/ Part Two: Sequence Searches and Alignment /Sequence Databases/ /Nucleic Acid Search Algorithms/ /Nucleic Acid Alignment Algorithms/ /Protein Alignment Algorithms/ Part Three: Phylogenetics /Understanding Phylogenetic Trees/ /Distance Algorithms/ /Parsimony Algorithms/ /Likelihood Algorithms/ /Bayesian Algorithms/ Part Four: Genomics /Whole Genome Assembly/ Part Five: Gene Expression Part Six: Protein Structure Protein Folding Protein structure prediction Secondary structure prediction Homology modelling De novo structure prediction Contact Prediction CASP Part Seven: Proteomics Part Eight: Metabolomics Part Nine: Metagenomics Part Ten: Biological sequences and biological diversity Chemical diversity, arising from sequence diversity, allows biological diversity How biological complexity is expressed in genomic differences Biological sequence data indicate a common ancestor for all living things Unique features of biological sequences derived from extremophiles The genetic origins of oxygen adapted life, mitochondria and chloroplasts The genetic origins of multi-cellularity A living species is defined as much by genetic diversity as by the genome of any particular individual How genetic variability within a species allows for speciation Part Eleven: Other types of biological data Medical informatics Environmental or population data Morphological data Relational databases and biological data Glossary Biology B 0%