ID Board Review/Human Immunodeficiency Virus (HIV) Infection/Complications of HIV/Opportunistic Infections (OIs)/OI Prevention

+Opportunistic Infection Prophylaxis: CD4 Levels and Other IndicationsInfectionCD4 Count, or Other IndicationsProphylaxisPJP CD4 <200 OR Oropharyngeal Candidiasis OR Hx of PCP Infx TMP/SMX ALT: Dapsone, Atovaquone, or PentamidineToxoplasma gondii CD4 <100 AND +IgG Ab TMP/SMX ALT: Dapsone + Pyrimethamine + Leucovorin ALT: Atovaquone +/- Pyrimethamine + LeucovorinHistoplasma capsulatum CD4 <150 AND living in endemic areas IntraconazoleVZV Close clontact w Chickenpox, or Shingles AND... No Hx of prior Dz, OR negative VZV Abs VariZIG OR IVIG (w/n 4 d of exposure) * It is no longer recommended to provide prophylaxis for Mycobacterium avium complex (MAC) MAC was previously covered when CD4 was < 50, however, this ppx was stopped due to risk of macrolide-resistance, and low incidence of MAC