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411 REFERENCE · Wikibooks

Radiation Oncology/Radiobiology/Radiosensitivity

Reference material by Wikibooks contributors. This retains its source identity and is not 411 news reporting.

Radiosensitivity is the relative susceptibility of cells, tissues, organs, organisms, or other substances to the injurious action of radiation In general, it has been found that cell radiosensitivity is directly proportional to the rate of cell division and inversely proportional to the degree of cell differentiation The most radio-sensitive cells: High division rate High metabolic rate Non-specialized type Well nourished Casarett classification: Group I Group II Group III Group IV Michalowski classification (PMID: 7127027): H-type (hierarchical): like hemopoietic tissues F-type (flexible): like liver parenchyma