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Radiation Oncology/RTOG Trials/0415
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RTOG 04-15 (PROSTATE)
Radiation_Oncology/Prostate/RTOG_Prostate
Title: A Phase III Randomized Study of Hypofractionated 3D-CRT/IMRT Versus Conventionally Fractionated 3D-CRT/IMRT in Patients With Favorable-Risk Prostate Cancer
Objective: Compare the disease-free survival (DFS) of patients with favorable-risk stage II prostate cancer treated with hypofractionated vs conventionally fractionated three-dimensional conformal radiotherapy (3D-CRT) or intensity-modulated radiotherapy (IMRT).
Protocol:
Arm 1: 73.8 Gy in 41 fractions
Arm 2: 70 Gy in 28 fractions
Eligibility:
T1-2c N0 M0, Gleason 2-6, PSA < 10
Enrollment Target: 1067 patients
Activated: April 18, 2006
Closed: December 11, 2009
Clinicaltrials.gov