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411 REFERENCE · Wikibooks

Nanotechnology/Biosensors

Reference material by Wikibooks contributors. This retains its source identity and is not 411 news reporting.

Navigate << Prev: Nano-bio Primer >< Main: Nanotechnology >> Next: Targeting Diseases __TOC__ Biosensors Biological sensor functionalisation, receptors and signals Assays for measuring the biochemical properties, such as immunesystem responses, specific proteins etc. DNA binding protein Functional group Receptor biochemistry Neuron The Biotin - Streptavidin binding is the strongest biochemical bond and often used when you need to demonstrate a sensor or bind different biomolecules together. Biofouling - by using certain polymers such as PEG or PLL-PEG, cell adhesion to surface can be drastically reduced. DNA Biosensors In the future, DNA will find use as a versatile material from which scientists can craft biosensors. DNA biosensors can theoretically be used for medical diagnostics, forensic science, agriculture, or even environmental clean-up efforts. No external monitoring is needed for DNA-based sensing devices. This is a significant advantage. DNA biosensors are complicated mini-machines—consisting of sensing elements, micro lasers, and a signal generator. At the heart of DNA biosensor function is the fact that two strands of DNA stick to each other by virtue of chemical attractive forces. On such a sensor, only an exact fit—that is, two strands that match up at every nucleotide position—gives rise to a fluorescent signal (a glow) that is then transmitted to a signal generator. Resources . <http://www.nigms.nih.gov>*Performance limits of nanobiosensors App. Phys. Lett. 88, 233120, 2006. References "The Chemistry of Health." The Chemistry of Health (2006): 42-43. National Institutes of Health and National Institute of General Medical Sciences. Web See also notes on editing this book about how to add references Nanotechnology/About#How_to_contribute.