Proteomics/Protein Separations- Electrophoresis/Timeline of Electrophoresis

__FORCETOC__ Introduction to Electrophoresis Gel Electrophoresis One Dimentional Gel Electrophoresis Two Dimensional Polyacrylamide Gel Electrophoresis(2D-PAGE) Differential in Gel Electrophoresis(DIGE) QPNC-PAGE Capillary Electrophoresis Timeline of Electrophoresis Databases Web Pages Online Applications Further Readings Timeline of Electrophoresis 1930s : Use of sucrose for gel electrophoresis. 1937 : The official launching of Tiselius' moving boundary electrophoresis (MBE). 1939 : Zone Electrophoresis 1950 : Rich in introducing novel methodologies in zone electrophoresis (ZE) 1950 : Agar Gel electrophoresis 1955 : Introduction of starch gels 1957 : Cellulose acetate Electrophoresis(CAc) by Kohn 1959 : Arrival of Acrylamide gels (Raymond and Winstraub) 1961 : Electrophoresis in silica gel by Honnegar 1961 : IsoElectricFocusing by Svensson 1964 : Electrophoresis in thin layer of sephadex beads by Fasella et.al 1964 : Ornstein and Davis introduced Disc-Gel Electrophoresis. 1969 : Beber and Osborn introduced denaturing agents i.e. SDS separation of protein subunit 1970 : Stacking gel and SDS by Laemmli was used to separate T4 phage proteins 1975 : 2-D gels :Isoelectric focussing and SDS gel electrophoresis by OFarrell. 1977 : Arrival of Sequencing gels 1970s : Arrival of Agarose gels 1980s : Immobilized pH gradients 1983 : Pulsed field gel electrophoresis was invented 1983 : Introduction of Capillary electrophoresis Next Section Databases References http://www.csupomona.edu/~nebuckley/Courses/Bio451/Lectures/Bio451Lecture4.htm Subcription Based References Righetti PG, Electrophoresis: the march of pennies, the march of dimes; Journal of Chromatography A. 2005 Jun 24;1079(1-2):24-40. Abstract[]