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Royal Australasian College of Physicians Examinations/Resources/Clinical Exam/Short Cases/Example Cases/Myaesthenia Gravis
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Myaesthenia Gravis
Stem: Please examine this person's eyes.
Key Features
Ptosis – may be asymmetrical. Worse after sustained upward gaze
Diplopia (+/- ophthalmoplegia) with sustained upward gaze
Bulbar weakness -> dysarthria (counting back from 20 to 1)
Neck extensor weakness
Proceed to
Proximal arm weakness with fatiguability
Look for thymectomy scar
Ask for spirometry / RFTs
Presentation
This patient has clinical features of myaesthenia gravis; evidenced by bilateral ptosis and diplopia on upward gaze; weakness of neck extension and fatiguability of shoulder abductors with a median sternotomy scar that suggests a previous thymectomy.
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