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Radiation Oncology/Thymic Carcinoma
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Thymic Carcinoma
Epidemiology
Pathology
Most thymic carcinomas are CD5+ CD70+ CD117+ (c-kit).
In contrast, thymomas are CD5- (except type B3). Squamous cell carcinomas of other organs are CD5- and CD70-. (Hodgkin lymphoma and nasopharyngeal carcinoma can be CD70+)
Neuroendocrine markers are positive in 2/3 of cases.
"World Health Organization Classification of Tumors: Pathology & Genetics: Tumors of the Lung, Pleura, Thymus and Heart", 2004, PDF