Radiation Oncology/Cosmetic Issues

Cosmetic Outcomes Charles T Lee et al. Cancer. 2019. Surgical excision, Mohs micrographic surgery, external-beam radiotherapy, or brachytherapy for indolent skin cancer: An international meta-analysis of 58 studies with 21,000 patients (PMID: 31355928) The objective of this study was to compare the cosmesis and recurrence rates of conventional excision (CE), Mohs micrographic surgery (MMS), external-beam radiation therapy (EBRT), or brachytherapy (BT), for basal cell carcinoma and squamous cell carcinoma of the skin The summary effect size for "good" cosmesis was 81% (95% CI, 70.6%-89.6%), 74.6% (95% CI, 63%-84.6%), and 97.6% (95% CI, 91.3%-100%) for CE, EBRT, and BT, respectively Good cosmesis was 96.0% in the only MMS study that reported cosmesis One-year recurrence rates were low throughout at 0.8% (95% CI, 0.3%-1.6%), 0.2% (95% CI, 0%-0.6%), 2% (95% CI, 1.3%-2.7%), and 0% (95% CI, 0%-0.5%) for CE, MMS, EBRT, and BT, respectively Conclusions (1) For T1-T2N0 skin cancers, BT and MMS have improved cosmesis over EBRT and CE (2) It is unclear whether this is because of treatment superiority or selection and reporting bias (3) Local control is similar among all modalities at 1 year Breast Radiotherapy after Oncoplastic Surgery Walter Paul Weber et al. Oncoplastic breast consortium recommendations for mastectomy and whole breast reconstruction in the setting of post-mastectomy radiation therapy. Breast. 2022 Jun;63:123-139. (PMID: 35366506) Gabrielle Metz et al. Breast Radiotherapy after Oncoplastic Surgery-A Multidisciplinary Approach. Cancers (Basel). 2022 Mar 25;14(7):1685. (PMID: 35406457) Radioactive Cosmetics [Article in English, Spanish] R M Díaz Díaz et al. Actas Dermosifiliogr (Engl Ed). 2020 Dec. Radioactive Cosmetics and Radiant Beauty (PMID: 32402372) Oncology Esthetics Serena Oliveri et al. Qual Life Res. 2019 Jun. A pilot study on aesthetic treatments performed by qualified aesthetic practitioners: efficacy on health-related quality of life in breast cancer patients (PMID: 30788654)