Radiation Oncology/NSCLC/RTOG Lung

RTOG Website Wikibooks list of RTOG trials +NSCLC: RTOG OPEN TRIALS NumberTitle 09-15 A Randomized Phase II Study Comparing 2 Stereotactic Body Radiation Therapy (SBRT) Schedules For Medically Inoperable Patients With Stage I Peripheral Non-Small Cell Lung Cancer 08-13 Seamless Phase I/II Study of Stereotactic Lung Radiotherapy (SBRT) For Early Stage, Centrally Located, Non-Small Cell Lung Cancer (NSCLC) In Medically Inoperable Patients 06-18 A Phase II Trial of Stereotactic Body Radiation Therapy (SBRT) in the Treatment of Patients with Operable Stage I/II Non-Small Cell Lung Cancer 06-17 A Randomized Phase III Comparison of Standard-Dose (60 Gy) Versus High Dose (74 Gy) Conformal Radiotherapy With Concurrent and Consolidation Carboplatin/Paclitaxel +/- Cetuximab (IND #103444) In Patients With Stage IIIA/IIIB Non-Small Cell Lung Cancer 02-29 A Phase II Trial Of Neoadjuvant Therapy With Concurrent Chemotherapy And High Dose Radiotherapy Followed by Surgical Resection And Consolidative Therapy For Locally Advanced Non-Small Cell Lung Carcinoma +NSCLC: RTOG CLOSED TRIALSNumberTitlePublication PMID XXXXXXXXXX 05-15 A Comparative Study Of Gross Tumor Volume Definition With Or Without PET Fusion For Patients With Non-Small Cell Lung Carcinoma 04-12 SWOG S0332 Phase III Randomized Trial of Preoperative Chemotherapy Versus Preoperative Concurrent Chemotherapy and Thoracic Radiotherapy Followed by Surgical Resection and Consolidation Chemotherapy in Favorable Prognosis Patients with Stage IIIA (N2) Non-Small Cell Lung Cancer CLOSED - POOR ACCRUAL 03-24 A Phase II Study Of Cetuximab (C225) In Combination With Chemoradiation In Patients With Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC) chapter link 21555682 02-36 A Phase II Trial of Stereotactic Body Radiation Therapy (SBRT) in the Treatment of Patients with Medically Inoperable Stage I/II Non-Small Cell Lung Cancer 02-35 Positron Emission Tomography Pre- and Post-treatment Assessment for Locally Advanced Non-small Cell Lung Carcinoma 02-14 A Phase III Comparison Of Prophylactic Cranial Irradiation Versus Observation In Patients With Locally Advanced Non-Small Cell Lung Cancer 02-13 A Phase I/II Trial of A Cox-2 Inhibitor, Celebrex (Celecoxib), with Limited Field Radiation for Intermediate Prognosis Patients with Locally Advanced Non-Small Cell Lung Cancer, with Analysis of Prognostic Factors CLOSED - ACCRUAL NOT MET 01-17 01-17 A Phase I/II Dose Intensification Study using Three Dimensional Conformal Radiation Therapy and Concurrent Chemotherapy for Patients with Inoperable, Non-Small Cell Lung Cancer 20368547 20457350 00-17 Clinicaltrials.gov A Phase I Study Of Gemcitabine, Carboplatin Or Gemcitabine, Paclitaxel And Radiation Therapy Followed By Adjuvant Chemotherapy For Patients With Favorable Prognosis Inoperable Stage IIIA/B Non-Small Cell Lung Cancer (NSCLC) 19096311 00-15 Clinicaltrials.gov SWOG S9900 A Randomized Phase III Trial Surgery Alone or Surgery Plus Preoperative Paclitaxel/Carboplatin in Clinical Stage IB (T2N0), II (T1-2N1, T3N0) and Selected IIIA (T3N1) Non Small Cell Lung Cancer (NSCLC) 20231678 99-09 Phase II Study of Postoperative Adjuvant Immunotherapy and Radiation in Patients with Completely Resected Stage II and Stage IIIA Non-Small Cell Lung Cancer 98-01 Clinicaltrials.gov A Phase III Study Of Amifostine Mucosal Protection For Patients With Favorable Prognosis Inoperable Stage II-IIIA/B Non-Small Cell Lung Cancer (NSCLC) Receiving Sequential Induction And Concurrent Hyperfractionated Radiotherapy With Paclitaxel And Carboplatin 15800308 18501528 19858383 97-05 Phase II Study of Postoperative Adjuvant Therapy in Patients With Completely Resected Stage II and Stage IIIA Non-Small Cell Lung Cancer 15908657 97-01 Phase III Randomized Trial of Radiation Therapy Alone versus Concurrent Chemotherapy plus Radiation Therapy for Poor-Risk Stage III Non-Small-Cell Lung Carcinoma CLOSED - POOR ACCRUAL 96-16 CALGB 9633 A Phase III Study of Adjuvant Chemotherapy After Resection for Patients with T2N0 Stage I Non-small Cell Carcinoma of the Lung 1880961495-11CALGB 9334, IntergroupSclerois of Pleural Effusions by Talc Thoracoscopy Versus Talc Slurry: A Phase III Study 94-10 94-10A Three-Arm Phase III Study of Concomitant Versus Sequential Chemotherapy and Thoracic Radiotherapy for Patients with Locally Advanced Inoperable Non-Small Cell Lung Cancer ASCO 200394-09 ECOG ECOG E4592LABORATORY/CLINICAL CORRELATIVE STUDIES IN NON-SMALL CELL LUNG CANCER. ANCILLARY STUDY TO RTOG 91-05/INT 0115 93-11 93-11 A Phase I-II Dose Escalation Study in Patients with Inoperable Non-Small Cell Lung Cancer 1566794993-09 93-09 INT 0139A Phase III Comparison Between Concurrent Chemotherapy Plus Radiotherapy, and Concurrent Chemotherapy plus Radiotherapy followed by Surgical Resection for Stage IIIA (N2) Non-Small Cell Lung Cancer 1963271692-04 12062596 91-06 Clinicaltrials.gov Phase I/II Study of Chemotherapy with CDDP/Oral VP-16 plus Radiotherapy in Patients with Locally Advanced, Inoperable non-Small Cell Lung Cancer 8648357 91-05 91-05INT 0115, ECOG E3590Randomized Trial of Postoperative Adjuvant Therapy in Patients with Completely Resected Stages II and IIIa Non-Small Cell Lung Cancer 1107167291-03 PULMONARY FUNCTION OF PATIENTS WITH RADIATION THERAPY FOR NON-SMALL LUNG CANCER 89-01 Phase III study comparing chemotherapy and radiotherapy with preoperative chemotherapy and surgical resection in patients with non-small-cell lung cancer with spread to mediastinal lymph nodes (N2) 12243809 See also: 7635796 (1995) — "The evolution of Radiation Therapy Oncology Group (RTOG) protocols for nonsmall cell lung cancer." Byhardt RW et al. Int J Radiat Oncol Biol Phys. 1995 Jul 30;32(5):1513-25.