(R)-dehydropantoate dehydrogenase

Class of enzymes (R)-dehydropantoate dehydrogenase 1.2.1.33 37250-96-7 0047509 In enzymology, (R)-dehydropantoate dehydrogenase (1.2.1.33) is an enzyme that catalyzes the chemical reaction 60% Q27102015 (R)-4-dehydropantoic acid + NAD+ reversible H2O H+ H+ H2O Q27098124 (R)-3,3-dimethylmalic acid + NADH The three substrates of this enzyme are (R)-4-dehydropantoic acid, oxidised nicotinamide adenine dinucleotide (NAD+), and water. Its products are (R)-3,3-dimethylmalic acid, reduced NADH, and a proton.1.2.1.33Magee PT, Snell EE 1966 The bacterial degradation of pantothenic acid. IV. Enzymatic conversion of aldopantoate to alpha-ketoisovalerate Biochemistry 5 409–16 4287371 10.1021/bi00866a004 2 This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-4-dehydropantoate:NAD+ 4-oxidoreductase. Other names in common use include D-aldopantoate dehydrogenase, D-2-hydroxy-3,3-dimethyl-3-formylpropionate:diphosphopyridine, and nucleotide (DPN+) oxidoreductase. This enzyme participates in pantothenate and coa biosynthesis. References Biology no Category:EC 1.2.1 Category:NADH-dependent enzymes Category:Enzymes of unknown structure