2-aminoadipate transaminase

Class of enzymes 2-aminoadipate transaminase 2.6.1.39 9033-00-5 0047536 In enzymology, 2-aminoadipate transaminase (2.6.1.39) is an enzyme that catalyzes the chemical reaction 65% Q27104392 L-2-aminoadipic acid + α-Ketoglutaric acid reversible 2-Oxoadipic acid + Q26995161 L-Glutamic acid The two substrates of this enzyme are L-2-aminoadipic acid and α-Ketoglutaric acid. Its products are 2-oxoadipic acid and L-glutamic acid.2.6.1.39Matsuda M, Ogur M 1969 Separation and specificity of the yeast glutamate-alpha-ketoadipate transaminase J. Biol. Chem. 244 3352–8 5792664 12 10.1016/S0021-9258(18)93133-9 free This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-2-aminoadipate:2-oxoglutarate aminotransferase. Other names in common use include alpha-aminoadipate aminotransferase, 2-aminoadipate aminotransferase, 2-aminoadipic aminotransferase, glutamic-ketoadipic transaminase, and glutamate-alpha-ketoadipate transaminase. This enzyme participates in lysine biosynthesis and lysine degradation. It employs one cofactor, pyridoxal phosphate.Voet Donald Biochemistry Voet Judith G. 2011 Wiley 978-0-470-91745-9 4th Hoboken, NJ 1040–41 Structural studies As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2DTV. References Biology no Category:EC 2.6.1 Category:Pyridoxal phosphate enzymes Category:Enzymes of known structure