(R)-aminopropanol dehydrogenase

Class of enzymes (R)-aminopropanol dehydrogenase 1.1.1.75 37250-13-8 0019147 In enzymology, a (R)-aminopropanol dehydrogenase (1.1.1.75) is an enzyme that catalyzes the chemical reaction 50% Q27098182 (2R)-1-aminopropan-2-ol + NAD+ reversible H+ H+ aminoacetone + NADH The two substrates of this enzyme are (2R)-1-aminopropan-2-ol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are aminoacetone, reduced NADH, and a proton.1.1.1.75Dekker EE, Swain RR 1968 Formation of Dg-1-amino-2-propanol by a highly purified enzyme from Escherichia coli Biochim. Biophys. Acta 158 306–7 4385233 2 10.1016/0304-4165(68)90150-5 https://deepblue.lib.umich.edu/bitstream/2027.42/33173/1/0000559.pdf 2027.42/33173 free Tuner JM 1966 Microbial metabolism of amino ketones. Aminoacetone formation from 1-aminopropan-2-ol by a dehydrogenase in Escherichia coli Biochem. J. 99 427–33 5329339 2 10.1042/bj0990427 1265012 Turner JM 1967 Microbial metabolism of amino ketones: l-1-Aminopropan-2-ol dehydrogenase and l-threonine dehydrogenase in Escherichia coli Biochem. J. 104 112–21 5340733 1 10.1042/bj1040112 1270551 This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-1-aminopropan-2-ol:NAD+ oxidoreductase. Other names in common use include L-aminopropanol dehydrogenase, 1-aminopropan-2-ol-NAD+ dehydrogenase, L(+)-1-aminopropan-2-ol:NAD+ oxidoreductase, 1-aminopropan-2-ol-dehydrogenase, DL-1-aminopropan-2-ol: NAD+ dehydrogenase, and L(+)-1-aminopropan-2-ol-NAD+/NADP+ oxidoreductase. This enzyme participates in glycine, serine and threonine metabolism. It requires potassium as a cofactor. References Biology no Category:EC 1.1.1 Category:NADH-dependent enzymes Category:Potassium enzymes Category:Enzymes of unknown structure