1-Testosterone

Chemical compound Boldenone changed changed 477208602 (5S,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-4,5,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one 1-Testosterone.svg skin-invert-image 225px 1-Testosterone molecule ball.png bg-transparent 225px Schedule III Androgen; Anabolic steroid Liver Urine changed ?? 65-06-5 correct FDA Y984BV1Q0G 579094 correct drugbank DB01481 correct chemspider 206590 correct EBI 59714 1-Testo; 1-T; δ1-Dihydrotestosterone; δ1-DHT; Dihydroboldenone 19 28 2 O=C4\C=C/[C@]1([C@@H](CC[C@@H]2[C@@H]1CC[C@@]3([C@@H](O)CC[C@@H]23)C)C4)C correct chemspider 1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,12,14-17,21H,3-6,8,10-11H2,1-2H3/t12-,14-,15-,16-,17-,18-,19-/m0/s1 correct chemspider OKJCFMUGMSVJBG-ABEVXSGRSA-N 1-Testosterone (abbreviated and nicknamed as 1-Testo, 1-T), also known as δ1-dihydrotestosterone (δ1-DHT), as well as dihydroboldenone, is a synthetic anabolic–androgenic steroid (AAS) and a 5α-reduced derivative of boldenone (Δ1-testosterone). It differs from testosterone by having a 1(2)-double bond instead of a 4(5)-double bond in its A ring.William Llewellyn Anabolics 9 https://books.google.com/books?id=3-FAQgAACAAJ 2009 Molecular Nutrition 978-0-9679304-7-3 22,135 It was legally sold online in the United States until 2005, when it was reclassified as a Schedule III drug. Side effects Anabolic steroid#Adverse effects Pharmacology Pharmacodynamics A 2006 study determined that 1-testosterone has a high androgenic and anabolic potency even without being metabolized, so it can be characterized as a typical anabolic steroid. 1-Testosterone binds in a manner that is highly selective to the androgen receptor (AR) and has a high potency to stimulate AR-dependent transactivation. In vivo, an equimolar dose of 1-testosterone has the same potency to stimulate the growth of the prostate, the seminal vesicles and the androgen-sensitive levator ani muscle as the reference anabolic steroid testosterone propionate, but, unlike testosterone propionate, 1-testosterone also increases liver weight. (The referenced study did not include humans, only animals).Friedel A, Geyer H, Kamber M, Laudenbach-Leschowsky U, Schänzer W, Thevis M, Vollmer G, Zierau O, Diel P 17beta-hydroxy-5alpha-androst-1-en-3-one (1-testosterone) is a potent androgen with anabolic properties Toxicol. Lett. 165 2 149–55 16621347 10.1016/j.toxlet.2006.03.001 August 2006 Chemistry List of androgens/anabolic steroids 1-Testosterone, IUPAC name 17β-hydroxy-5α-androst-1-en-3-one, also known as 4,5α-dihydro-δ1-testosterone (Δ1-DHT) or as 5α-androst-1-en-17β-ol-3-one, is a synthetic androstane steroid and a derivative of dihydrotestosterone (DHT). Derivatives Two prohormones of 1-testosterone are 1-androstenediol and 1-androstenedione, the latter of which may be synthesized from stanolone acetate.Zhang H, Qiu Z An efficient synthesis of 5α-androst-1-ene-3,17-dione Steroids 71 13–14 1088–90 17123559 10.1016/j.steroids.2006.09.008 December 2006 53258890 Detection in body fluids Doping with 1-testosterone can be detected in urine samples using gas chromatography. S. Jain, A. Beotra and T. Kaur http://proceedings.live-record.de/proceedings_13_pdf/13_407.pdf A Case Study: Detection of 1-Testosterone in Urine by GC-MSD Recent Advances in Doping Analysis 13 2005 407–410 2011-06-18 https://web.archive.org/web/20110825032543/http://proceedings.live-record.de/proceedings_13_pdf/13_407.pdf 2011-08-25 dead References 2 Category:Abandoned drugs Category:Secondary alcohols Category:Androgens Category:Androstanes Category:Ketones