10-Deacetylbaccatin

10-Deacetylbaccatin III Deacetylbaccatin.png 200px 10-Deacetylbaccatin-III-3D-balls.png 200 10-Deacetylbaccatin III molecule 1,7β,10β,13α-Tetrahydroxy-9-oxo-5β,20-epoxytax-11-ene-2α,4-diyl 2-benzoate 4-acetate (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-4,6,9,11-Tetrahydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-12,12b-diyl 12b-acetate 12-benzoate 10-Deacetylbaccatin III10-Deacetylbaccatine III correct CAS 32981-86-5 correct FDA 4K6EWW2Z45 correct EBI 393912 154272 correct chemspider 135935 correct EBI 18193 correct chemspider 1S/C29H36O10/c1-14-17(31)12-29(36)24(38-25(35)16-9-7-6-8-10-16)22-27(5,23(34)21(33)20(14)26(29,3)4)18(32)11-19-28(22,13-37-19)39-15(2)30/h6-10,17-19,21-22,24,31-33,36H,11-13H2,1-5H3/t17-,18-,19+,21+,22-,24-,27+,28-,29+/m0/s1 correct chemspider YWLXLRUDGLRYDR-ZHPRIASZSA-N CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O C29H36O10 544.59 g/mol colorless solid 234 insoluble soluble in methanol 10-Deacetylbaccatins are a series of closely related natural organic compounds isolated from the yew tree (Genera Taxus). 10-deacetylbaccatin III is a precursor to the anti-cancer drug docetaxel (Taxotere). 10-deacetylbaccatin III 10-O-acetyltransferase converts 10-deacetylbaccatin to baccatin III:Walker K, Croteau R 2000 Molecular cloning of a 10-deacetylbaccatin III-10-O-acetyl transferase cDNA from Taxus and functional expression in Escherichia coli Proc. Natl. Acad. Sci. U.S.A. 97 583–7 10639122 10.1073/pnas.97.2.583 2 15373 2000PNAS...97..583W free 70% 10-Deacetylbaccatin 1.5 + class=skin-invert-image acetyl-CoA Baccatin III 1.5 + coenzyme A References External links 6712096 - 7-Epi-10-Deacetylbaccatin III 9872117 - 10-Deacetylbaccatin V 5316348 - 10-Deacetylbaccatin VI 5317065 - 13-Epi-10-Deacetylbaccatin III 15957452 - 13-[3-(2-Naphthyl)prop-2-enoyl]-2-debenzoyl-2-(4-methoxybenzoxyl)-10-deacetylbaccatin III 15957458 - 10-N,N-Dimethylglycyl-13-[3-(2-Naphthyl)prop-2-enoyl]-10-deacetylbaccatin III Category:Benzoate esters Category:Secondary alcohols Category:Tertiary alcohols Category:Ketones Category:Diterpenes Category:Acetate esters