(S)-cheilanthifoline synthase

Class of enzymes (S)-cheilanthifoline synthase 1.14.21.2 138791-27-2 0047053 In enzymology, (S)-cheilanthifoline synthase (1.14.21.2) is an enzyme that catalyzes the chemical reaction 55% scoulerine + NADPH O2 2 H2O cheilanthifoline + NADP+ The three substrates of this enzyme are (S)-scoulerine, reduced nicotinamide adenine dinucleotide phosphate (NADPH), and oxygen. Its products are cheilanthifoline, oxidised NADP+, and water.1.14.21.2 Bauer W, Zenk MH 1991 Two methylenedioxy bridge-forming cytochrome P-450 dependent enzymes are involved in (S)-stylopine biosynthesis Phytochemistry 30 2953–2961 10.1016/S0031-9422(00)98230-X 9 1991PChem..30.2953B This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and the other dehydrogenated. The systematic name of this enzyme class is (S)-scoulerine,NADPH:oxygen oxidoreductase (methylenedioxy-bridge-forming). This enzyme is also called (S)-scoulerine oxidase (methylenedioxy-bridge-forming). The enzyme participates in alkaloid biosynthesis. In recent development, it has been determined that cheilanthifoline synthase can be cloned. Researchers are currently researching how this cloning might be found in yeast. https://pubmed.ncbi.nlm.nih.gov/28633475/ References Biology no Category:EC 1.14.21 Category:NADPH-dependent enzymes Category:Enzymes of unknown structure