2-dehydro-3-deoxy-6-phosphogalactonate aldolase

Class of enzymes 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 4.1.2.21 9030-99-3 0008674 The enzyme 2-dehydro-3-deoxy-6-phosphogalactonate aldolase (4.1.2.21) catalyzes the chemical reaction 2-dehydro-3-deoxy-D-galactonate 6-phosphate pyruvate + D-glyceraldehyde 3-phosphate This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming). Other names in common use include 6-phospho-2-keto-3-deoxygalactonate aldolase, phospho-2-keto-3-deoxygalactonate aldolase, 2-keto-3-deoxy-6-phosphogalactonic aldolase, phospho-2-keto-3-deoxygalactonic aldolase, 2-keto-3-deoxy-6-phosphogalactonic acid aldolase, (KDPGal)aldolase, 2-dehydro-3-deoxy-D-galactonate-6-phosphate, and D-glyceraldehyde-3-phosphate-lyase. This enzyme participates in galactose metabolism. Structural studies As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2V81 and 2V82. References 1 Shuster CW 1966 Carbohydrate Metabolism 2-Keto-3-deoxy-6-phosphogalactonic acid aldolase 9 524–528 10.1016/0076-6879(66)09104-3 Methods in Enzymology 978-0-12-181809-8 Biology no Category:EC 4.1.2 Category:Enzymes of known structure