(R)-limonene 6-monooxygenase

Class of enzymes (R)-limonene 6-monooxygenase 1.14.14.53 221461-49-0 (R)-limonene 6-monooxygenase (1.14.14.53) is an enzyme that catalyzes the chemical reaction 50% Q27888324 (R)-limonene + NADPH + H+ O2 H2O Q27089408 (+)-trans-carveol + NADP+ The four substrates of this enzyme are (+)-(R)-limonene, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen, and a proton. Its products are (+)-trans-carveol, oxidised NADP+, and water.1.14.14.53Bouwmeester HJ, Gershenzon J, Konings MC, Croteau R 1998 Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration Of enzyme activities and their changes with development Plant Physiol. 117 901–12 9662532 10.1104/pp.117.3.901 3 34944 This enzyme is a cytochrome P450 protein containing heme. This oxidoreductase, which uses molecular oxygen as oxidant, is in a group with systematic name (R)-limonene,NADPH:oxygen oxidoreductase (6-hydroxylating). Other names in common use include (+)-limonene-6-hydroxylase, and (+)-limonene 6-monooxygenase. It is part of the biosynthesis pathway to (+)-carvone in caraway. Croteau R 1999 Cytochrome P-450 dependent (+)-limonene-6-hydroxylation in fruits of caraway (Carum Carvi) Phytochemistry 50 243–248 10.1016/S0031-9422(98)00516-0 2 See also CYP2C19 (S)-limonene 6-monooxygenase which converts the opposite enantiomer of limonene to (–)-trans-carveol References 1 Biology no Category:EC 1.14.14 Category:NADPH-dependent enzymes Category:Enzymes of unknown structure