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1,2-dihydrovomilenine reductase

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Class of enzymes 1,2-dihydrovomilenine reductase 1.3.1.73 0050615 In enzymology, a 1,2-dihydrovomilenine reductase (1.3.1.73) is an enzyme that catalyzes the chemical reaction 17-O-acetylnorajmaline + NADP+ 1,2-dihydrovomilenine + NADPH + H+ Thus, the two substrates of this enzyme are 17-O-acetylnorajmaline and NADP+, whereas its 3 products are 1,2-dihydrovomilenine, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 17-O-acetylnorajmaline:NADP+ oxidoreductase. This enzyme participates in indole and ipecac alkaloid biosynthesis. References 1 Gao S, von Schumann G, Stockigt J 2002 A newly-detected reductase from Rauvolfia closes a gap in the biosynthesis of the antiarrhythmic alkaloid ajmaline Planta Medica 68 906–11 12391554 10.1055/s-2002-34935 10 2002PlMed..68..906G Biology no Category:EC 1.3.1 Category:NADPH-dependent enzymes Category:Enzymes of unknown structure