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(+)-car-3-ene synthase
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Class of enzymes
(+)-car-3-ene synthase 4.2.3.107
(+)-Car-3-ene synthase (EC 4.2.3.107, 3-carene cyclase, 3-carene synthase, 3CAR, (+)-3-carene synthase) is an enzyme with systematic name geranyl-diphosphate diphosphate-lyase [cyclizing, (+)-car-3-ene-forming]. Savage TJ, Croteau R Biosynthesis of monoterpenes: regio- and stereochemistry of (+)-3-carene biosynthesis Archives of Biochemistry and Biophysics 305 2 581–7 September 1993 8373196 10.1006/abbi.1993.1464 Savage TJ, Ichii H, Hume SD, Little DB, Croteau R Monoterpene synthases from gymnosperms and angiosperms: stereospecificity and inactivation by cysteinyl- and arginyl-directed modifying reagents Archives of Biochemistry and Biophysics 320 2 257–65 July 1995 7625832 10.1016/0003-9861(95)90008-x Savage TJ, Hatch MW, Croteau R Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase The Journal of Biological Chemistry 269 6 4012–20 February 1994 10.1016/S0021-9258(17)41735-2 8307957 free Fäldt J, Martin D, Miller B, Rawat S, Bohlmann J Traumatic resin defense in Norway spruce (Picea abies): methyl jasmonate-induced terpene synthase gene expression, and cDNA cloning and functional characterization of (+)-3-carene synthase Plant Molecular Biology 51 1 119–33 January 2003 12602896 10.1023/A:1020714403780 21153303 Hamberger B, Hall D, Yuen M, Oddy C, Hamberger B, Keeling CI, Ritland C, Ritland K, Bohlmann J Targeted isolation, sequence assembly and characterization of two white spruce (Picea glauca) BAC clones for terpenoid synthase and cytochrome P450 genes involved in conifer defence reveal insights into a conifer genome BMC Plant Biology 9 106 August 2009 1 19656416 2729077 10.1186/1471-2229-9-106 2009BMCPB...9..106H free Hall DE, Robert JA, Keeling CI, Domanski D, Quesada AL, Jancsik S, Kuzyk MA, Hamberger B, Borchers CH, Bohlmann J An integrated genomic, proteomic and biochemical analysis of (+)-3-carene biosynthesis in Sitka spruce (Picea sitchensis) genotypes that are resistant or susceptible to white pine weevil The Plant Journal 65 6 936–48 March 2011 21323772 10.1111/j.1365-313x.2010.04478.x This enzyme catalyses the following chemical reaction
geranyl diphosphate (+)-car-3-ene + diphosphate
The enzyme reacts with (3S)-linalyl diphosphate twice as rapidly as geranyl diphosphate.
References
External links
(+)-car-3-ene+synthase
Biology no
Category:EC 4.2.3