2-Bromodeschloroketamine

Chemical compound 2-(2-Bromophenyl)-2-(methylamino)cyclohexan-1-one Bromoketamine Structure.svg skin-invert-image 150 Schedule I NpSG Class B 120807-70-7 correct CAS correct FDA BG9ADQ6XT9 71588007 62958449 13 16 1 1 1 CNC1(CCCCC1=O)C2=CC=CC=C2Br 1S/C13H16BrNO/c1-15-13(9-5-4-8-12(13)16)10-6-2-3-7-11(10)14/h2-3,6-7,15H,4-5,8-9H2,1H3 XPMMBFIMXKSQIQ-UHFFFAOYSA-N 2-Bromodeschloroketamine (also known as 2-Br-2'-Oxo-PCM and bromoketamine) is a chemical compound of the arylcyclohexylamine class, which is an analog of the dissociative anesthetic drug ketamine in which the chlorine atom has been replaced with a bromine atom. Its specific pharmacological activities have not been studied. It is used in scientific research as a comparison or control compound in studies into the metabolism of ketamine and norketamine. Stiller RL, Dayton PG, Perel JM, Hug CC Gas chromatographic analysis of ketamine and norketamine in plasma and urine: nitrogen-sensitive detection Journal of Chromatography 232 2 305–14 November 1982 6818238 10.1016/s0378-4347(00)84170-5 Rodriguez Rosas ME, Patel S, Wainer IW Determination of the enantiomers of ketamine and norketamine in human plasma by enantioselective liquid chromatography-mass spectrometry Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 794 1 99–108 August 2003 12888202 10.1016/s1570-0232(03)00420-3 Wang PF, Neiner A, Lane TR, Zorn KM, Ekins S, Kharasch ED Halogen Substitution Influences Ketamine Metabolism by Cytochrome P450 2B6: In Vitro and Computational Approaches Molecular Pharmaceutics 16 2 898–906 February 2019 30589555 10.1021/acs.molpharmaceut.8b01214 9121441 It has been sold online as a designer drug.December 2020 See also 2-Fluorodeschloroketamine 3-Fluorodeschloroketamine Deschloroketamine Methoxyketamine Trifluoromethyldeschloroketamine References Category:Arylcyclohexylamines Category:Designer drugs Category:Ketones Category:Dissociative drugs Category:2-Bromophenyl compounds