(Methyl-Co(III) methanol-specific corrinoid protein):coenzyme M methyltransferase

Class of enzymes (Methyl-Co(III) methanol-specific corrinoid protein):coenzyme M methyltransferase 2.1.1.246 (Methyl-Co(III) methanol-specific corrinoid protein):coenzyme M methyltransferase (2.1.1.246, methyltransferase 2, mtaA (gene)) is an enzyme with systematic name methylated methanol-specific corrinoid protein:coenzyme M methyltransferase. LeClerc GM, Grahame DA Methylcobamide:coenzyme M methyltransferase isozymes from Methanosarcina barkeri. Physicochemical characterization, cloning, sequence analysis, and heterologous gene expression The Journal of Biological Chemistry 271 31 18725–31 August 1996 8702528 10.1074/jbc.271.31.18725 free Harms U, Thauer RK Methylcobalamin: coenzyme M methyltransferase isoenzymes MtaA and MtbA from Methanosarcina barkeri. Cloning, sequencing and differential transcription of the encoding genes, and functional overexpression of the mtaA gene in Escherichia coli European Journal of Biochemistry 235 3 653–9 February 1996 8654414 10.1111/j.1432-1033.1996.00653.x free Sauer K, Thauer RK Methanol:coenzyme M methyltransferase from Methanosarcina barkeri. Zinc dependence and thermodynamics of the methanol:cob(I)alamin methyltransferase reaction European Journal of Biochemistry 249 1 280–5 October 1997 9363780 10.1111/j.1432-1033.1997.t01-1-00280.x Sauer K, Harms U, Thauer RK Methanol:coenzyme M methyltransferase from Methanosarcina barkeri. Purification, properties and encoding genes of the corrinoid protein MT1 European Journal of Biochemistry 243 3 670–7 February 1997 9057830 10.1111/j.1432-1033.1997.t01-1-00670.x Sauer K, Thauer RK Methanol:coenzyme M methyltransferase from Methanosarcina barkeri -- substitution of the corrinoid harbouring subunit MtaC by free cob(I)alamin European Journal of Biochemistry 261 3 674–81 May 1999 10215883 10.1046/j.1432-1327.1999.00355.x This enzyme catalyses the following chemical reaction [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M methyl-CoM + [Co(I) methanol-specific corrinoid protein] Free methylcob(I)alamin can substitute for the corrinoid protein in vitro. References External links (methyl-Co(III)+methanol-specific+corrinoid+protein):coenzyme+M+methyltransferase Biology no Category:EC 2.1.1