1-Hydroxy-7-azabenzotriazole

HOAt changed 477207891 1-hydroxy-7-aza-benzotriazole.svg 150px Skeletal formula of HOAt 1-Hydroxy-7-azabenzotriazole molecule spacefill from xtal.png 150 Space-filling model of the HOAt molecule 3H-[1,2,3]Triazolo[4,5-b]pyridin-3-ol 1/C5H4N4O/c10-9-5-4(7-8-9)2-1-3-6-5/h1-3,10H FPIRBHDGWMWJEP-UHFFFAOYAJ correct chemspider 1S/C5H4N4O/c10-9-5-4(7-8-9)2-1-3-6-5/h1-3,10H correct chemspider FPIRBHDGWMWJEP-UHFFFAOYSA-N correct CAS 39968-33-7 correct FDA TX8XYH09H0 181649 n1cccc2nnn(O)c12 correct chemspider 158005 5 4 4 1 0.973 g/mL 213-216°C 01 05 06 07 danger H204 H301 H302 H315 H318 H319 H335 P210 P240 P250 P261 P264 P270 P271 P280 P301+P310 P301+P312 P302+P352 P304+P340 P305+P351+P338 P310 P312 P321 P330 P332+P313 P337+P313 P362 P370+P380 P372 P373 P374 P401 P403+P233 P405 P501 GHS: Sigma Aldrich 445452 1-Hydroxy-7-azabenzotriazole (HOAt) is a triazole used as a peptide coupling reagent. 10.1021/ja00063a082 1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive Journal of the American Chemical Society 115 10 4397–4398 1993 Carpino Louis A It suppresses racemization that can otherwise occur during the reaction.Amide bond formation: beyond the myth of coupling reagents Valeur Eric Bradley Mark Chemical Society Reviews 2009 38 2 606–631 10.1039/b701677h 19169468 HOAt has a melting point of 213-216 °C.https://www.chemicalbook.com/ChemicalProductProperty_EN_CB3256884.htm HOAt Chemical Book January 30, 2019 References Category:Peptide coupling reagents Category:Triazolopyridines Category:Reagents for biochemistry Category:Hydroxylamines