2-Coumarate reductase

Class of enzymes 2-coumarate reductase 1.3.1.11 37251-10-8 0047788 In enzymology, 2-coumarate reductase or melilotate dehydrogenase (1.3.1.11) is an enzyme that catalyzes the chemical reaction 60% Q11751633 2-hydroxybenzenepropanoic acid + NAD+ reversible H+ H+ o-Coumaric acid 2-coumaric acid + NADH The two substrates of this enzyme are 2-hydroxybenzenepropanoic acid (melilotic acid) and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are 2-coumaric acid, reduced NADH, and a proton.1.3.1.11 Levy CC, Weinstein GD The metabolism of coumarin by a microorganism. II. The reduction of o-coumaric acid to melilotic acid Biochemistry 3 12 1944–7 December 1964 14269315 10.1021/bi00900a027 This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-(2-hydroxyphenyl)propanoate:NAD+ oxidoreductase. This enzyme participates in phenylalanine metabolism. References Biology no Category:EC 1.3.1 Category:NADH-dependent enzymes Category:Enzymes of unknown structure Category:Hydroxycinnamic acids metabolism