(−)-Isopiperitenone reductase

Class of enzymes (−)-isopiperitenone reductase 1.3.1.82 (−)-Isopiperitenone reductase (1.3.1.82) is an enzyme with systematic name (+)-cis-isopulegone:NADP+ oxidoreductase that is found in peppermint. Croteau R, Venkatachalam KV Metabolism of monoterpenes: demonstration that (+)-cis-isopulegone, not piperitenone, is the key intermediate in the conversion of (−)-isopiperitenone to (+)-pulegone in peppermint (Mentha piperita) Archives of Biochemistry and Biophysics 249 2 306–15 September 1986 3755881 10.1016/0003-9861(86)90007-x Ringer KL, McConkey ME, Davis EM, Rushing GW, Croteau R Monoterpene double-bond reductases of the (−)-menthol biosynthetic pathway: isolation and characterization of cDNAs encoding (−)-isopiperitenone reductase and (+)-pulegone reductase of peppermint Archives of Biochemistry and Biophysics 418 1 80–92 October 2003 13679086 10.1016/s0003-9861(03)00390-4 It catalyses the following chemical reaction: 45% Q27089423 (-)-isopiperitenone + NADPH forward H+ H+ Q27104394 (+)-cis-isopulegone + NADP+ The three substrates of this enzyme are (-)-isopiperitenone, reduced nicotinamide adenine dinucleotide phosphate (NADPH), and a proton. It converts them to (+)-cis-isopulegone and oxidised NADP+.1.3.1.82 References External links (−)-isopiperitenone+reductase Biology no Category:EC 1.3.1