2,5-Dimethoxy-4-acetylamphetamine

DOAc DOAc structure.svg skin-invert-image 250px Serotonin 5-HT2 receptor modulator None 23983771 34948069 2,5-Dimethoxy-4-acetylamphetamine; 4-Acetyl-2,5-dimethoxyamphetamine; DOAc; DOAC 1-[4-(2-aminopropyl)-2,5-dimethoxyphenyl]ethanone 13 19 1 3 CC(CC1=CC(=C(C=C1OC)C(=O)C)OC)N 1S/C13H19NO3/c1-8(14)5-10-6-13(17-4)11(9(2)15)7-12(10)16-3/h6-8H,5,14H2,1-4H3 NWWLLPGDGZOZAT-UHFFFAOYSA-N 2,5-Dimethoxy-4-acetylamphetamine (DOAc) is a serotonin 5-HT2 receptor modulator of the amphetamine and DOx families. Nelson DL, Lucaites VL, Wainscott DB, Glennon RA Comparisons of hallucinogenic phenylisopropylamine binding affinities at cloned human 5-HT2A, -HT(2B) and 5-HT2C receptors Naunyn Schmiedebergs Arch Pharmacol 359 1 1–6 January 1999 9933142 10.1007/pl00005315 Its affinities (Ki) for the human serotonin 5-HT2 receptors are 80.5nM for the serotonin 5-HT2A receptor, 313nM for the serotonin 5-HT2B receptor, and 91.3nM for the serotonin 5-HT2C receptor. These affinities are much lower than those of many other DOx derivatives, such as DOB, but are very similar to those of 3,4,5-trimethoxyamphetamine (TMA). DOAc is a controlled substance in Canada under phenethylamine blanket-ban language.Controlled Drugs and Substances Act Department of Justice Canada https://laws-lois.justice.gc.ca/eng/acts/c-38.8/FullText.html 19 January 2026 See also DOx (psychedelics) References External links DOAC - Isomer Design Category:Acetyl compounds Category:DOx (psychedelics) Category:Serotonin receptor modulators