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2,6-dihydroxypseudooxynicotine hydrolase
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Class of enzymes
2,6-dihydroxypseudooxynicotine hydrolase 3.7.1.19
2,6-dihydroxypseudooxynicotine hydrolase (3.7.1.19) is an enzyme with systematic name 1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one hydrolase. Gherna RL, Richardson SH, Rittenberg SC The bacterial oxidation of nicotine. VI. The metabolism of 2,6-dihydroxypseudooxynicotine The Journal of Biological Chemistry 240 9 3669–74 September 1965 10.1016/S0021-9258(18)97197-8 free 5835946 Sachelaru P, Schiltz E, Igloi GL, Brandsch R An alpha/beta-fold C--C bond hydrolase is involved in a central step of nicotine catabolism by Arthrobacter nicotinovorans Journal of Bacteriology 187 24 8516–9 December 2005 16321959 1317030 10.1128/jb.187.24.8516-8519.2005 This enzyme catalyses the following chemical reaction
1-(2,6-dihydroxypyridin-3-yl)-4-(methylamino)butan-1-one + H2O 2,6-dihydroxypyridine + 4-methylaminobutanoate
The enzyme is present in the soil bacterium Arthrobacter nicotinovorans.
References
External links
2,6-dihydroxypseudooxynicotine+hydrolase
Biology no
Category:EC 3.7.1