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1-Decanol
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changed 477207517 Merck Index, 12th Edition, 2911. 1-Decanol 1-Decanol.png 300px skin-invert Skeletal formula 1-Decanol-3D-vdW.png Space-filling model bg-transparent Decan-1-ol decyl alcoholn-decyl alcoholcapric alcoholepal 10antakagent 504 DeOn-DeOHnDeOHnDeOH correct chemspider correct EBI 28903 7882 correct FDA 89V4LX791F correct kegg C01633 1/C10H21OH/c1-2-3-4-5-6-7-8-9-10-11/h11H,2-10H2,1H3 MWKFXSUHUHTGQN-UHFFFAOYAN correct EBI 25363 correct chemspider 1S/C10H21OH/c1-2-3-4-5-6-7-8-9-10-11/h11H,2-10H2,1H3 correct chemspider MWKFXSUHUHTGQN-UHFFFAOYSA-N correct CAS 112-30-1 OCCCCCCCCCC 8174 10 22 1 0.8297 g/cm3 12.048 mPa.s (@ 25 °C) 4.57 6.4 232.9 Viscous liquid 37 mg/L at 25°Chttps://pubchem.ncbi.nlm.nih.gov/compound/1-decanol 1-Decanol 07 09 Warning 315 319 411 412 264 264+265 273 280 302+352 305+351+338 321 332+317 337+317 362+364 391 501 2 2 0 108 Oxford MSDS
1-Decanol is a straight chain fatty alcohol with ten carbon atoms and the molecular formula C10H22O 1 or CH3(CH2)9OH. It is a colorless to light yellow viscous liquid that is insoluble in water and has an aromatic odor.Material Safety Data Sheet - Decyl alcohol, 99% https://fscimage.fishersci.com/msds/11356.htm live https://archive.today/20210901171536/https://fscimage.fishersci.com/msds/11356.htm 2021-09-01 2021-09-01 fscimage.fishersci.com The interfacial tension against water at 20 °C is 8.97 mN/m.
Production
Decanol can be prepared by the hydrogenation of decanoic acid, which occurs in modest quantities in coconut oil (about 10%) and palm kernel oil (about 4%). It may also be produced synthetically via the Ziegler process.
Uses
Decanol is used in the manufacture of plasticizers, lubricants, surfactants and solvents. Its ability to permeate the skin has led to it being investigated as a penetration enhancer for transdermal drug delivery.Kanikkannan N Singh Mandip Skin permeation enhancement effect and skin irritation of saturated fatty alcohols International Journal of Pharmaceutics November 2002 248 1–2 219–228 10.1016/S0378-5173(02)00454-4 12429475Williams Adrian C Barry Brian W Penetration enhancers Advanced Drug Delivery Reviews March 2004 56 5 603–618 10.1016/j.addr.2003.10.025 15019749
Safety
Like other medium chain fatty alcohols, 1-decanol is able to permeate the skin which can lead to irritation.
References
Category:Fatty alcohols
Category:Primary alcohols
Category:Alkanols
Category:Decyl compounds