1-hydroxy-2-naphthoate hydroxylase

Class of enzymes 1-hydroxy-2-naphthoate hydroxylase 1.14.13.135 1-hydroxy-2-naphthoate hydroxylase (1.14.13.135, 1-hydroxy-2-naphthoic acid hydroxylase) is an enzyme with systematic name 1-hydroxy-2-naphthoate,NAD(P)H:oxygen oxidoreductase (2-hydroxylating, decarboxylating). Deveryshetty J, Phale PS Biodegradation of phenanthrene by Alcaligenes sp. strain PPH: partial purification and characterization of 1-hydroxy-2-naphthoic acid hydroxylase FEMS Microbiology Letters 311 1 93–101 October 2010 20727010 10.1111/j.1574-6968.2010.02079.x free This enzyme catalyses the following chemical reaction 65% Q27104334 1-hydroxy-2-naphthoic acid + NADH O2 + H+ H2O Q27096830 1,2-naphthalenediol + NAD+ + CO2 The four substrates of this enzyme are 1-hydroxy-2-naphthoic acid, reduced nicotinamide adenine dinucleotide (NADH), oxygen, and a proton. Its products are 1,2-naphthalenediol, oxidised NAD+, water, and carbon dioxide.1.14.13.135 It is involved in chrysene degradation in some bacteria. Nayak AS, Sanjeev Kumar S, Santosh Kumar M, Anjaneya O, Karegoudar TB A catabolic pathway for the degradation of chrysene by Pseudoxanthomonas sp. PNK-04 FEMS Microbiology Letters 320 2 128–34 July 2011 21545490 10.1111/j.1574-6968.2011.02301.x free References External links 1-hydroxy-2-naphthoate+hydroxylase Biology no Category:EC 1.14.13