1,2,3-Tris(4-hydroxybutyroyloxy)propane

vanc 6 1,2,3-Tris(4-hydroxybutyroyloxy)propane.svg skin-invert-image 280px GABAB receptor agonist; GHB receptor agonist; Hypnotic None 53806632 2,3-bis(4-hydroxybutanoyloxy)propyl 4-hydroxybutanoate 15 26 9 C(CC(=O)OCC(COC(=O)CCCO)OC(=O)CCCO)CO 1S/C15H26O9/c16-7-1-4-13(19)22-10-12(24-15(21)6-3-9-18)11-23-14(20)5-2-8-17/h12,16-18H,1-11H2 FMEHQSVBVKIXBB-UHFFFAOYSA-N 1,2,3-Tris(4-hydroxybutyroyloxy)propane is a chemical compound which acts as a sustained-release prodrug for gamma-hydroxybutyrate (GHB), consisting of three molecules of gamma-hydroxybutyrate joined to a glycerol core by readily metabolised ester links. It was developed as a potential agent for the treatment of sleep disorders such as narcolepsy. US 7572605 Mamelak M, Houghton WC, Reardan DT, Miller BL Gamma-hydroxybutyrate compositions containing carbohydrate, lipid or amino acid carriers 2005-07-18 2009-08-11 2005-07-18 2000-09-22 Orphan Medical Inc Jazz Pharmaceuticals Inc https://patents.google.com/patent/US7572605B2 See also List of investigational narcolepsy and hypersomnia drugs 1,4-Butanediol (1,4-BD) 1,6-Dioxecane-2,7-dione γ-Butyrolactone (GBL) Aceburic acid Ethyl acetoxy butanoate Glyceryl-tris-3-hydroxybutyrate (3GHB) Tributyrin Valiloxybate References Category:Esters Category:GABA analogues Category:GABAB receptor agonists Category:Γ-Hydroxybutyric acid Category:Gamma hydroxycarboxylic acids Category:GHB receptor agonists Category:Hypnotics Category:Neurotransmitter precursors Category:Prodrugs Category:Sedatives Category:Triglycerides