(S)-3-amino-2-methylpropionate transaminase

Class of enzymes (S)-3-amino-2-methylpropionate transaminase 2.6.1.22 9031-95-2 0047298 (S)-3-amino-2-methylpropionate transaminase (2.6.1.22) is an enzyme that catalyzes the reversible chemical reaction 70% Q27088673 (S)-3-aminoisobutyric acid + α-Ketoglutaric acid α-ketoglutaric acid reversible Q27103355 3(S)-methylmalonaldehydic acid + Q26995161 L-glutamic acid The two substrates of this enzyme characterised from kidney and liver are (S)-3-aminoisobutyric acid and α-ketoglutaric acid. Its products are 3(S)-methylmalonaldehydic acid and L-glutamic acid.Kakimoto Y, Kanazawa A, Taniguchi K, Sano I 1968 Beta-aminoisobutyrate-alpha-ketoglutarate transaminase in relation to beta-aminoisobutyric aciduria Biochim. Biophys. Acta 156 374–80 5641913 2 10.1016/0304-4165(68)90267-5Tamaki N, Sakata SF, Matsuda K Purification, Properties, and Sequencing of Aminoisobutyrate Aminotransferases from Rat Liver 2000 Branched-Chain Amino Acids, Part B 324 376–89 10989446 10.1016/S0076-6879(00)24247-X Methods in Enzymology 978-0-12-182225-5 This enzyme is a transferase, specifically a transaminase, which transfer nitrogenous groups. The systematic name of this enzyme class is (S)-3-amino-2-methylpropanoate:2-oxoglutarate aminotransferase. Other names in common use include L-3-aminoisobutyrate transaminase, beta-aminobutyric transaminase, L-3-aminoisobutyric aminotransferase, and beta-aminoisobutyrate-alpha-ketoglutarate transaminase. It participates in valine, leucine and isoleucine degradation.2.6.1.22 References Biology no Category:EC 2.6.1 Category:Enzymes of unknown structure