17-alpha-hydroxyprogesterone aldolase

Class of enzymes June 2022 17α-Hydroxyprogesterone aldolase 4.1.2.30 62213-24-5 0047442 In enzymology, a 17α-hydroxyprogesterone aldolase (4.1.2.30) is an enzyme that catalyzes the chemical reaction 17α-hydroxyprogesterone androst-4-en-3,17-dione + acetaldehyde Hence, this enzyme has one substrate, 17α-hydroxyprogesterone, and two products, androst-4-en-3,17-dione and acetaldehyde. This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 17α-hydroxyprogesterone acetaldehyde-lyase (4-androstene-3,17-dione-forming). Other names in common use include C-17/C-20-lyase, and 17α-hydroxyprogesterone acetaldehyde-lyase. This enzyme participates in androgen and estrogen metabolism. References 1 Nowotny E, Sananez RD, Nattero G, Yantorno C, Faillaci MG 1974 Bioconversion of steroids in vitro by testes from autoimmunized rabbits Hoppe-Seyler's Z. Physiol. Chem. 355 716–20 4435747 6 10.1515/bchm2.1974.355.1.716 Biology no Category:EC 4.1.2 Category:Enzymes of unknown structure