2-Bromopyridine

2-Brpyridine.png 120px 2-bromopyridine-from-xtal-3D-bs-17.png 2-bromopyridine-from-xtal-3D-sf.png 2-Bromopyridine correct CAS 109-04-6 correct FDA 7Z7MLC4VD8 203-641-6 7973 7685 51574 331374 c1ccnc(c1)Br 1/C5H4BrN/c6-5-3-1-2-4-7-5/h1-4H IMRWILPUOVGIMU-UHFFFAOYAP 1S/C5H4BrN/c6-5-3-1-2-4-7-5/h1-4H IMRWILPUOVGIMU-UHFFFAOYSA-N C5H4NBr 158.00 colorless liquid 194.8 °C 0.71 (for C5H4(Br)NH+) Linnell Robert Notes- Dissociation Constants of 2-Substituted Pyridines The Journal of Organic Chemistry 1960 25 2 290 10.1021/jo01072a623 2-Chloropyridine3-Bromopyridine 2-Bromopyridine is an aryl bromide and isomer of bromopyridine with the formula BrC5H4N. It is a colorless liquid that is used as an intermediate in organic synthesis. It can be prepared from 2-aminopyridine via diazotization followed by bromination.Allen, C. F. H.; Thirtle, John R. "2-Bromopyridine" Organic Syntheses 1946, volume 26, pp. 16-18. 10.15227/orgsyn.026.0016 free Reactions Like 2-chloropyridine, 2-bromopyridine is very weakly basic. 2-Bromopyridine reacts with butyllithium to give 2-lithiopyridine,10.15227/orgsyn.088.0079 Synthesis of Lithium 2-Pyridyltriolborate and ITS Cross-Coupling Reaction with Aryl Halides Organic Syntheses 2011 88 79 Yasunori Yamamoto Juugaku Sugai Miho Takizawa Norio Miyaura Norio Miyaura free which is a versatile reagent.Satinder V. Kessar, Paramjit Singh, Dmitry Zuev, Zhenlei Song, Ya Wu "2-Lithiopyridine" e-EROS Encyclopedia of Reagents for Organic Synthesis, 2015. 10.1002/047084289X.rl025.pub3 Pyrithione can be prepared in a two-step synthesis from 2-bromopyridine by oxidation to the N-oxide with a suitable peracid followed by substitution using either sodium dithionite or sodium sulfide with sodium hydroxide to introduce the thiol functional group. 1-Hydroxypyridine-2(1H)-thione David W. Knight Jens Hartung 1-Hydroxypyridine-2(1H)-thione 15 September 2006 10.1002/047084289X.rh067.pub2 John Wiley & Sons Encyclopedia of Reagents for Organic Synthesis 0471936235 Applications Organometallic addition to benzophenone followed by catalytic hydrogenation is the synthesis of pipradrol. References Category:2-Pyridyl compounds Category:Bromoarenes