16S rRNA (guanine1207-N2)-methyltransferase

Class of enzymes 16S rRNA (guanine1207-N2)-methyltransferase 2.1.1.172 16S rRNA (guanine1207-N2)-methyltransferase (2.1.1.172, m2G1207 methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine1207-N2)-methyltransferase. Tscherne JS, Nurse K, Popienick P, Ofengand J Purification, cloning, and characterization of the 16 S RNA m2G1207 methyltransferase from Escherichia coli The Journal of Biological Chemistry 274 2 924–9 January 1999 9873033 10.1074/jbc.274.2.924 free Sunita S, Purta E, Durawa M, Tkaczuk KL, Swaathi J, Bujnicki JM, Sivaraman J Functional specialization of domains tandemly duplicated within 16S rRNA methyltransferase RsmC Nucleic Acids Research 35 13 4264–74 2007 17576679 1934991 10.1093/nar/gkm411 This enzyme catalyses the following chemical reaction S-adenosyl-L-methionine + guanine1207 in 16S rRNA S-adenosyl-L-homocysteine + N2-methylguanine1207 in 16S rRNA The enzyme reacts well with 30S subunits reconstituted from 16S RNA transcripts and 30S proteins but is almost inactive with the corresponding free RNA. References External links 16S+rRNA+(guanine1207-N2)-methyltransferase Biology no Category:EC 2.1.1