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411 REFERENCE · Wikipedia

2,2'-Dipyridyldisulfide

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413095043 2,2′-Dipyridyldisulfide 2,2'-Dipyridyldisulfide.svg Skeletal formula of DPS 2,2'-Dipyridyldisulfide-3D-spacefill.png Space-filling model of the DPS molecule 2,2′-Disulfanediyldipyridine 1,2-Di(pyridin-2-yl)disulfane (not recommended)2,2′-Dipyridyldisulfide2,2′-DipyridyldisulphideAldrithiol-2 correct chemspider 58603 1/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H HAXFWIACAGNFHA-UHFFFAOYAJ c1ccnc(c1)SSc2ccccn2 correct EBI 143170 118678 65093 218-343-1 correct chemspider 1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H correct chemspider HAXFWIACAGNFHA-UHFFFAOYSA-N 2127-03-9 correct FDA L6X912UPBU S(Sc1ncccc1)c2ncccc2 10 8 2 2 56 to 58 Irritant (Xi) 07 Warning 315 319 335 261 264 271 280 302+352 304+340 305+351+338 312 321 332+313 337+313 362 403+233 405 501 2,2′-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols Futaki S. and Kitagawa K. Peptide-Unit Assembling Using Disulfide Cross-Linking - a New Approach for Construction of Protein Models 1994 Tetrahedron Lett. 35 8 1267–1270 10.1016/0040-4039(94)88040-9 Aldrichimica Acta Special Reagents for Thiol Groups 4 3 33–46 and activating carboxylic acid for coupling reactions, as in the following reaction: Org. Synth. Thalmann A., Oertle K. and Gerlach H Ricinelaidic acid lactone 1985 7 470 10.15227/orgsyn.063.0192 free 600px Uses It is also used in molecular biology as an oxidising agent, for example to oxidise free thiols to form disulfide bonds in proteins. References Category:Organic disulfides Category:2-Pyridyl compounds Category:Reagents for organic chemistry