2-Chloroethyl chloroformate

2-chloroethyl chloroformate.svg 2-Chloroethyl carbonochloridate β-chloroethyl chloroformate 627-11-2 correct 210-982-4 correct FDA 4D32H07Z9I 12305 11802 3277 ClC(=O)OCCCl 1S/C3H4Cl2O2/c4-1-2-7-3(5)6/h1-2H2 SVDDJQGVOFZBNX-UHFFFAOYSA-N 3 4 2 2 colourless liquid pungentcymitquimica.com CAS 627-11-2: Carbonochloridic acid, 2-chloroethyl ester https://cymitquimica.com/cas/627-11-2/ cymitquimica.com 22 March 2026 1.3847 g/cm3 155 1.4483 05 06 07 Danger 301 314 315 319 331 335 260 264 264+265 270 271 280 301+316 301+330+331 302+352 302+361+354 304+340 305+351+338 305+354+338 316 319 321 330 332+317 337+317 362+364 363 403+233 405 501 70 https://www.sigmaaldrich.com/GB/en/sds/aldrich/252514?userType=anonymous Sigmaaldrich.com Safety data sheet: 2-chloroethyl chloroformate 2025-06-30 1-Chloroethyl chloroformate Chloromethyl chloroformate Ethyl chloroformate chloroformates 2-Chloroethyl chloroformate is an organochlorine compound with the chemical formula ClCOOCH2CH2Cl. It is a colourless liquid with a pungent odor. It has a structure consisting of ethyl chloroformate with a chlorine atom as a substituent on the position 2 on the ethyl group. Synthesis 2-Chloroethyl chloroformate is the sole product of the reaction between ethylene oxide and phosgene in the presence of a small amount of pyridine.10.1039/JR9570002735 530. The reaction of carbonyl chloride with 1 : 2-epoxides 1957 Jones J. Idris Journal of the Chemical Society (Resumed) 2735 Uses 2-Chloroethyl chloroformate is commonly used as a reagent,10.1002/047084289X.rn01309 β-Chloroethyl Chloroformate Encyclopedia of Reagents for Organic Synthesis 2011 Mousseau James J. 978-0-471-93623-7 Wu Yikang Shen Xin A high-yielding low-cost facile synthesis of 2-oxazolidinones chiral auxiliaries Tetrahedron: Asymmetry 11 21 2000 10.1016/S0957-4166(00)00415-8 4359–4363 especially for making derivatives of amines and carboxylic acids for analysis by gas chromatography.10.1002/jhrc.1240151203 The derivatization of fatty acids by (Chloro)alkyl chloroformates in non-aqueous and aqueous media for GC analysis 1992 Vreeken Rob J. Jager Maria E. Ghijsen Rudy T. Brinkman Udo A. Th. Journal of High Resolution Chromatography 15 12 785–790 10.1016/S0378-4347(98)00136-4 Chloroformates in gas chromatography as general purpose derivatizing agents 1998 Hušek Petr Journal of Chromatography B: Biomedical Sciences and Applications 717 1–2 57–91 9832240 References Category:Chloroformates Category:Chloroethyl compounds