2-Hydroxy-4-methoxybenzaldehyde

2-Hydroxy-4-methoxybenzaldehyde.svg 150px Chemical structure of 2-hydroxy-4-methoxybenzaldehyde 2-Hydroxy-4-methoxybenzaldehyde 4-Methoxysalicylaldehyde 673-22-3 correct CAS correct FDA 2N395P88LW 69600 COC1=CC(=C(C=C1)C=O)O 62803 1S/C8H8O3/c1-11-7-3-2-6(5-9)8(10)4-7/h2-5,10H,1H3 WZUODJNEIXSNEU-UHFFFAOYSA-N 8 8 3 2-Hydroxy-4-methoxybenzaldehyde is a chemical compound and a positional isomer of vanillin. A fragrant phenolic compound found as a major constituent of the essential oils of the root bark and stem bark of some members of the subfamily Periplocoideae of the plant family Apocynaceae. These include the roots of Decalepis hamiltonii,Thangadurai Devarajan Anitha Sreeyapureddy Pullaiah Thammineni Reddy Ponnathota Narasimha Ramachandraiah Oleti Siva Essential Oil Constituents and in Vitro Antimicrobial Activity of Decalepis hamiltonii Roots against Foodborne Pathogens. Journal of Agricultural and Food Chemistry 2002 50 11 3147–3149 10.1021/jf011541q 12009977 2002JAFC...50.3147T https://pubs.acs.org/doi/abs/10.1021/jf011541q 1 May 2026 subscription Nagarajan S. Jagan Mohan Rao L. Gurudutt K.N. Chemical composition of the volatiles of Decalepis hamiltonii (Wight & Arn). Flavour and Fragrance Journal 2001 16 1 27–29 10.1002/1099-1026(200101/02)16:1<27::aid-ffj937>3.0.co;2-f https://onlinelibrary.wiley.com/doi/abs/10.1002/1099-1026(200101/02)16:1%3C27::aid-ffj937%3E3.0.co;2-f 1 May 2026 subscription Decalepis salicifolia,RODRIGUES VEREENA KUMAR AMIT GOKUL SIVARAMAN SHUKLA ASHUTOSH K. RAVIKUMAR KALIAMOORTHY SUNDARESAN VELUSAMY Decalepis salicifolia (Bedd. ex Hook. f.) Venter: A steno-endemic and critically endangered medicinal and aromatic plant from Western Ghats, India Journal of Biosciences 2021 46 2 44 10.1007/s12038-021-00162-6 https://www.ias.ac.in/article/fulltext/jbsc/046/0044 1 May 2026 Hemidesmus indicus,Nagarajan S. Jagan Mohan Rao L. Gurudutt K.N. Chemical composition of the volatiles of Hemidesmus indicus R. Br. Flavour and Fragrance Journal 2001 16 3 212–214 10.1002/ffj.985 https://onlinelibrary.wiley.com/doi/abs/10.1002/ffj.985 1 May 2026 subscription Sreekumar S. Seeni S. Pushpangadan P. Production of 2-hydroxy 4-methoxy benzaldehyde using root cultures of Hemidesmus indicus Biotechnology Letters 1998 20 7 631–635 10.1023/A:1005354003727 https://link.springer.com/article/10.1023/A:1005354003727 1 May 2026 subscription Mondia whitei,Mukonyi Kavaka W. Ndiege Isaiah O. 2-Hydroxy-4-methoxybenzaldehyde: Aromatic taste-modifying compound from Mondia whytei Skeels. Bulletin of the Chemical Society of Ethiopia 2001 15 2 137–142 https://www.researchgate.net/publication/262858756 1 May 2026 Periploca angustifolia, Periploca sepiumLee N-H Lee H-S Periploca root oils as potent, diphenolase-selective tyrosinase inhibitors: chemotype profiling and non-competitive mechanism of 4-methoxy-2-hydroxybenzaldehyde Journal of the Science of Food and Agriculture 2026 106 2 1185–1194 10.1002/jsfa.70241 41048180 2026JSFA..106.1185L https://doi.org/10.1002/jsfa.70241 2 May 2026 subscription and Zygostelma benthamiiPongpan N. Kaewnoi A. Vallisuta O. Antiviral activity on selective bitter plants against Influenza A (H1N1) virus The 8th International Conference on Natural Products, Asian Society for Natural Products 2023 2 1 P-7 10.23177/NATPRO8.2023.06.22.012 http://165.194.131.91/asnp/NATPRO8%20009.pdf 2 May 2026 and the stem bark of Periploca graeca.Huang Mingjin Shen Shoumao Luo Chunli Ren Yan Genus Periploca (Apocynaceae): A Review of Its Classification, Phytochemistry, Biological Activities and Toxicology Molecules 2019 24 15 2749 10.3390/molecules24152749 free 31362394 6696197 Some of these plants also contain toxic cardenolides. Urolithin M7, one of the urolithins, has also been synthesized from 2-hydroxy-4-methoxybenzaldehyde using the inverse electron-demand Diels–Alder reaction. 10.1055/s-0030-1261203 An Inverse Electron-Demand Diels-Alder-Based Total Synthesis of Urolithin M7 2011 Bodwell Graham Pottie Ian Nandaluru Penchal Synlett 2011 15 2245 See also Vanillin 2-Hydroxy-5-methoxybenzaldehyde Isovanillin ortho-Vanillin References Category:Salicylaldehyde derivatives