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1-Aminotetralin
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1-Aminotetralin.svg skin-invert-image 150px 1,2,3,4-Tetrahydronaphthalen-1-amine 1-AT; 1-Amino-1,2,3,4-tetrahydronaphthalene 2217-40-5 correct CAS 17067 220-973-7 18066 1S/C10H13N/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-2,4,6,10H,3,5,7,11H2 JRZGPXSSNPTNMA-UHFFFAOYSA-N C1CC(C2=CC=CC=C2C1)N O7A3GV2PNX
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1-Aminotetralin (1-AT), also known as 1-amino-1,2,3,4-tetrahydronaphthalene, is a chemical compound and one of the possible positional isomers of aminotetralin.Trachsel D. Lehmann D. Enzensperger C. Phenethylamine: von der Struktur zur Funktion Phenethylamines: From Structure to Function 1 Nachtschatten-Verlag Solothurn Nachtschatten-Science 2013 978-3-03788-700-4 858805226 https://books.google.com/books?id=-Us1kgEACAAJ de 263 It consists of a tetralin core with an amino substituent on one of the carbon atoms.
Derivatives
1-Aminotetralin is the parent structure of a number of drugs, including the following:Shah Bhumi M. Kachhadiya Radhika N. Shaping the future of medicine through diverse therapeutic applications of tetralin derivatives Medicinal Chemistry Research 34 1 2025 1054-2523 10.1007/s00044-024-03331-y 86–113 https://www.researchgate.net/publication/385559544
15em Dasotraline
Desmethylsertraline
Ethonam
Lometraline
LP-12
LP-44
Sertraline
SR 59230A
Tametraline
Tochergamine
Tramazoline is another related compound.
See also
2-Aminotetralin
Aminoindane
References
External links
1-Aminotetralin - Isomer Design