2-methylisocitrate dehydratase

Class of enzymes 2-methylisocitrate dehydratase 4.2.1.99 170780-51-5 0047456 The enzyme 2-methylisocitrate dehydratase (4.2.1.99) catalyzes the chemical reaction (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate (Z)-but-2-ene-1,2,3-tricarboxylate + H2O This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase [(Z)-but-2-ene-1,2,3-tricarboxylate-forming]. This enzyme is also called (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate hydro-lyase. This enzyme participates in propanoate metabolism. References 1 10.1271/bbb.59.1825 Aoki H, Uchiyama H, Umetsu H, Tabuchi T 1995 Isolation of 2-methylisocitrate dehydratase, a new enzyme serving in the methylcitric acid cycle for propionate metabolism, from Yarrowia lipolytica Biosci. Biotechnol. Biochem. 59 10 1825–1828 free 10.1271/bbb.59.2013 Tabuchi T, Umetsu H, Aoki H, Uchiyama H 1995 Characteristics of 2-methylisocitrate dehydratase, isolated from Yarrowia lipolytica, in comparison to aconitase Biosci. Biotechnol. Biochem. 59 11 2013–2017 free Biology no Category:EC 4.2.1 Category:Enzymes of unknown structure