16β,17α-Epiestriol

epiestriol (set index) 16β,17α-Epiestriol.svg skin-invert-image 250px Estra-1,3,5(10)-triene-3,16β,17α-triol (1S,2S,3aS,3bR,9bS,11aS)-11a-Methyl-2,3,3a,3b,4,5,9b,10,11,11a-decahydro-1H-cyclopenta[a]phenanthrene-1,2,7-triol 793-89-5 correct FDA 13628086 21252247 Oc1ccc2[C@H]3CC[C@]4(C)[C@@]5([C@]6C[C@H]4[C@@H]3CCc2c1).O6.O5 1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16+,17-,18+/m1/s1 18 24 3 16β,17α-Epiestriol, or 16,17-epiestriol, also known as 16β-hydroxy-17α-estradiol, as well as estra-1,3,5(10)-triene-3,16β,17α-triol, is a minor and weak endogenous steroidal estrogen that is related to 17α-estradiol and estriol.Vitamins and Hormones https://books.google.com/books?id=iQZgQRUI_CgC&pg=PA233 18 April 1972 Academic Press 978-0-08-086626-0 233–Ryō Satō Ryūichi Katō Microsomes, drug oxidations, and drug toxicity https://books.google.com/books?id=t7PwAAAAMAAJ 1982 Japan Scientific Societies Press 978-0-471-87285-6 273 Along with estriol, 16β,17α-epiestriol has been detected in the urine of women during the late pregnancy stage. It shows preferential affinity for the ERβ over the ERα. Zhu BT, Han GZ, Shim JY, Wen Y, Jiang XR Quantitative structure-activity relationship of various endogenous estrogen metabolites for human estrogen receptor alpha and beta subtypes: Insights into the structural determinants favoring a differential subtype binding Endocrinology 147 9 4132–50 2006 16728493 10.1210/en.2006-0113 free See also 16β-Epiestriol 17α-Epiestriol Epimestrol References Category:Estranes Category:Estrogens