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2-Phenyl-2-propanol
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2-Phenyl-2-propanol 2-Phenyl-2-propanol Structural Formula V1.svg 2-Phenylpropan-2-ol 617-94-7 131607 3185495 11556 210-539-5 12053 JE030BGE05 1S/C9H12O/c1-9(2,10)8-6-4-3-5-7-8/h3-7,10H,1-2H3 BDCFWIDZNLCTMF-UHFFFAOYSA-N CC(C)(C1=CC=CC=C1)O 136.19 g/mol White to pale yellow odorless solid2-Phenyl-2-propanol 33610 617-94-7 2017-04-16 28 - 32 C K 0.973 g/cm3 202 Soluble in ethanol and benzeneGail Vance Civille, B. Thomas Carr 2015 978-1-4822-0867-2 204 CRC Press Sensory Evaluation Techniques, Fifth Edition TdnhAwAAQBAJ 204 yes 1.49146 (20 °C)P30802 2-Phenyl-2-propanol, 97% 2017-04-16 C9H12O Practically insoluble 07 4300mg/kg (rabbit, transdermal); 1300mg/kg (rat, oral) Danger H302 H315 H319 P280 P301 + 330 +331 P302 +352 P305+ 351 +338 362
2-Phenyl-2-propanol is a chemical compound that belongs to the alcohol group. It is a derivative of cumene.
Synthesis
2-Phenyl-2-propanol can be synthesized through Grignard reaction between phenylmagnesium bromide and acetone.William Brown Christopher Foote Brent Iverson Eric Anslyn 2008 978-0-495-38857-9 568 Cengage Learning Organic Chemistry mTHQB7MkUFsC 568 yesAlbany College of Pharmacy and Health Sciences: Preparation of 2-Phenyl-2-propanol (Grignard Reaction) https://web.archive.org/web/20200803205206/http://organicchem.org/oc2web/lab/exp/grig/grigdesacetone.html 2020-08-03 , retrieved 16 April 2017.
Properties
2-Phenyl-2-propanol is a white to pale-yellow, odorless solid which is combustible yet difficult to ignite and barely dissolves in water.
Applications
2-Phenyl-2-propanol can either be applied in organic syntheses, or be reactants or intermediates in agrochemical, medical, and dyestuff fields.A15580 2-Phenyl-2-propanol, 98+% 2017-04-16
2-Phenyl-2-propanol is the main metabolite of cumene, and therefore 2-phenyl-2-propanol can serve as a biomarker of cumene.2-Phenyl-2-propanol in Urin [Biomonitoring Methods in German language, 2012] 2002 10.1002/3527600418.bi9882d0020 978-3-527-60041-0 Wiley-VCH Verlag & Co. KGaA The MAK-Collection for Occupational Health and Safety Knecht U. 1–10 free https://repository.publisso.de/resource/frl:6456048/data
Hazards
According to a report of Federal Institute for Risk Assessment in 2008, there is strong evidence that 2-phenyl-2-propanol may lead to allergic reactions for humans.BfR: Verbraucher sollten Plastik-Clogs mit starkem Geruch meiden, Stellungnahme Nr. 047/2008 des BfR of 5 November 2008.
References
Category:Tertiary alcohols
Category:Phenyl compounds
Category:Isopropyl compounds