2,4,6-Trinitrobenzenesulfonic acid

changed changed 477198445 2,4,6-Trinitrobenzene Sulfonic Acid trinitrobenzenesulfonic acid.png 160px skin-invert 2,4,6-Trinitrobenzenesulfonic-acid-3D-balls.png 160 2,4,6-Trinitrobenzenesulfonic acid molecule 2,4,6-Trinitrobenzene-1-sulfonic acid Picrylsulfonic acid; Trinitrobenzene sulfonate; TNBS 2508-19-2 correct CAS 572358 correct EBI 53063 3586251 correct chemspider 10577 correct drugbank 219-717-7 1051138 correct kegg 11045 correct FDA 8T3HQG2ZC4 0386 1/C6H3N3O9S/c10-7(11)3-1-4(8(12)13)6(19(16,17)18)5(2-3)9(14)15/h1-2H,(H,16,17,18) NHJVRSWLHSJWIN-UHFFFAOYAG correct chemspider 1S/C6H3N3O9S/c10-7(11)3-1-4(8(12)13)6(19(16,17)18)5(2-3)9(14)15/h1-2H,(H,16,17,18) correct chemspider NHJVRSWLHSJWIN-UHFFFAOYSA-N O=S(=O)(O)c1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)[N+]([O-])=O 0.955 g/cm3 6 3 3 9 1 2 4 4 OX 01 05 06 Danger 317 334 261 272 280 285 302+352 304+341 321 333+313 342+311 363 501 Picric acidTrinitroanisole Trinitrobenzenesulfonic acid (C6H3N3O9S) is a nitroaryl oxidizing acid and explosive, used in biochemical research. Uses Its primary usage is primarily to neutralize peptide terminal amino groups in scientific research.Trinitrobenzenesulfonic Acid, Comparative Toxicogenomics Database. Occasionally it is used as a detonator for certain other explosive compounds.April 2026 The compound is currently being investigated for its effects on the immune system. The Journal of Experimental Medicine 192 1 2000 41–52 Treatment of Experimental (Trinitrobenzene Sulfonic Acid) Colitis by Intranasal Administration of Transforming Growth Factor (Tgf)-β1 Plasmid: TGF-β1–Mediated Suppression of T Helper Cell Type 1 Response Occurs by Interleukin (Il)-10 Induction and IL-12 Receptor β2 Chain Downregulation Atsushi Kitani Ivan J. Fuss Kazuhiko Nakamura Owen M. Schwartz Takashi Usui Warren Strober 10.1084/jem.192.1.41 10880525 1887715 It is used to induce colitis in the colon of laboratory animals in order to model inflammatory bowel disease and post-infectious irritable bowel syndrome.Antoniou Efstathios Margonis Georgios Antonios Angelou Anastasios Pikouli Anastasia Argiri Paraskevi Karavokyros Ioannis Papalois Apostolos Pikoulis Emmanouil 2016-08-19 The TNBS-induced colitis animal model: An overview Annals of Medicine and Surgery 11 9–15 10.1016/j.amsu.2016.07.019 2049-0801 5021709 27656280 Safety precautions The compound has generally not been investigated for toxicity. However, the primary hazard of working with 2,4,6-trinitrobenzenesulfonic acid is the risk of explosion. Similar to other polynitroaryl acids (e.g. picric acid, TNT), 2,4,6-trinitrobenzenesulfonic acid can explode when heated strongly and mechanically disturbed, even in the presence of common phlegmatizers such as water. It will rapidly heat to ignition if exposed to medium-strong reducing agents, including hydrides, sulfides, and nitrides.Transport safety advice, via NOAA Office of Response and Restoration's CAMEO Chemicals, version 3.1.0 revision 2. Accessed 10 April 2026. References Category:Explosive chemicals Category:Nitrobenzene derivatives Category:Benzenesulfonic acids Category:Liquid explosives