2-Methyl-5-hydroxytryptamine

Chemical compound changed 477214316 3-(2-aminoethyl)-2-methyl-1H-indol-5-ol 2-Methyl-5-hydroxytryptamine.svg skin-invert-image 250px 2-methylserotonin 3D.png bg-transparent 200px changed ?? 78263-90-8 1574 218 correct chemspider 1518 correct FDA D77Z9HJT2U correct kegg C13665 correct EBI 31085 correct EBI 266591 11 14 2 1 Oc1cc2c(cc1)[nH]c(c2CCN)C correct chemspider 1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3 correct chemspider WYWNEDARFVJQSG-UHFFFAOYSA-N 2-Methyl-5-hydroxytryptamine (2-methylserotonin, 2-methyl-5-HT) is a tryptamine derivative closely related to the neurotransmitter serotonin which acts as a moderately selective full agonist at the 5-HT3 receptor. 10.1002/ardp.19933261110 Elz S, Zimmermann H, Rehse K Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines. Archiv der Pharmazie 326 11 893–899 1993 8274071 1671270 Craig DA, Eglen RM, Walsh LK, Perkins LA, Whiting RL, Clarke DE 5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum. Naunyn-Schmiedeberg's Arch Pharmacol 342 1 9–16 1990 2402303 10.1007/bf00178965 24743785 http://www.acnp.org/g4/GN401000039/Ch039.html Serotonin Receptor Subtypes and Ligands 2008-04-11 Glennon RA, Dukat M, Westkaemper RB 2000-01-01 American College of Neurophyscopharmacology https://web.archive.org/web/20080421160353/http://www.acnp.org/g4/GN401000039/Ch039.html 21 April 2008 live See also 5-Carboxamidotryptamine 5-Methoxytryptamine α-Methyl-5-hydroxytryptamine References Category:5-HT3 agonists Category:2-Alkyltryptamines Category:5-Hydroxytryptamines Category:Serotonin receptor agonists