2-oxoglutarate carboxylase

Class of enzymes 2-Oxoglutarate carboxylase 6.4.1.7 In enzymology, a 2-oxoglutarate carboxylase (6.4.1.7) is an enzyme that catalyzes the chemical reaction ATP + 2-oxoglutarate + HCO3- ADP + phosphate + oxalosuccinate The 3 substrates of this enzyme are ATP, 2-oxoglutarate, and HCO3-, whereas its 3 products are ADP, phosphate, and oxalosuccinate. This enzyme belongs to the family of ligases, specifically those forming carbon-carbon bonds. The systematic name of this enzyme class is '''. Other names in common use include oxalosuccinate synthetase, carboxylating factor for ICDH (incorrect), CFI, and OGC'''. References 1 Aoshima M, Ishii M, Igarashi Y 2004 A novel biotin protein required for reductive carboxylation of 2-oxoglutarate by isocitrate dehydrogenase in Hydrogenobacter thermophilus TK-6 Mol. Microbiol. 51 791–8 14731279 10.1046/j.1365-2958.2003.03863.x 3 free Aoshima M, Igarashi Y 2006 A novel oxalosuccinate-forming enzyme involved in the reductive carboxylation of 2-oxoglutarate in Hydrogenobacter thermophilus TK-6 Mol. Microbiol. 62 748–59 17076668 10.1111/j.1365-2958.2006.05399.x 3 free Biology no Category:EC 6.4.1 Category:Enzymes of unknown structure