1,3-Dichloropropan-2-ol

1,3-Dichloropropan-2-ol.svg 150px 1,3-Dichloropropan-2-ol 1,3-Dichloropropanol-2; 1,3-Dichloroisopropyl alcohol; 1,3-Dichloro-2-propanol; 1,3-Dichloroisopropanol; Glycerol-α,γ-dichlorohydrin; α-Dichlorohydrin; 1,3-DCP; DC2P 96-23-1 7289 202-491-9 UB1400000 2750 18917 468581 C14399 21106535 C(C(CCl)O)Cl 0F4P2VQC07 1S/C3H6Cl2O/c4-1-3(6)2-5/h3,6H,1-2H2 DEWLEGDTCGBNGU-UHFFFAOYSA-N 3 6 2 1 Colorless liquid32050 Phenol-like 1.39 g/cm3 (20 °C) -4 175 110 g/L (20 °C) 74 110 mg/kg (oral, rat)1080 mg/kg (dermal, rabbit) 06 07 08 Danger 301 311 312 336 350 370 373 201 202 260 261 264 270 271 280 281 301+310 302+352 304+340 307+311 308+313 312 314 321 322 330 361 363 403+233 405 501 1,3-Dichloropropan-2-ol (1,3-DCP) is an organic compound with the formula HOCH2CHClCH2Cl. It is a colorless liquid. It is an intermediate in the production of epichlorohydrin. https://www.ncbi.nlm.nih.gov/books/NBK373196/ Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-Water 1,3-Dichloro-2-propanol 2013 International Agency for Research on Cancer 10.1021/es903383a 20163179 Identifying New Persistent and Bioaccumulative Organics Among Chemicals in Commerce Environmental Science & Technology 44 7 2277–2285 2010 Howard Philip H. Muir Derek C. G. 2010EnST...44.2277H free 1,3-DCP is a believed to be a carcinogen and mutagen. https://oehha.ca.gov/media/downloads/proposition-65/13-dcphida.pdf Evidence on the Carcinogenicity of 1,3-Dichloro-2-Propanol (1,3-DCP; α,γ-Dichlorohydrin) Reproductive and Cancer Hazard Assessment Branch Office of Environmental Health Hazard Assessment, California Environmental Protection Agency June 2010 The International Agency for Research on Cancer classifies it as a Group 2B carcinogen ("possibly carcinogenic to humans"). http://monographs.iarc.fr/ENG/Classification/latest_classif.php List of Classifications International Agency for Research on Cancer 2018-03-13 2017-06-10 https://web.archive.org/web/20170610015529/http://monographs.iarc.fr/ENG/Classification/latest_classif.php dead Along with 3-monochloropropane-1,2-diol (3-MCPD), 1,3-DCP is found in some Asian style sauces such as soy sauce and oyster sauce. 10.1021/acs.jafc.6b05051 28064506 Simultaneous Analysis of 3-MCPD and 1,3-DCP in Asian Style Sauces Using QuEChERS Extraction and Gas Chromatography–Triple Quadrupole Mass Spectrometry Journal of Agricultural and Food Chemistry 65 4 981–985 2017 Genualdi Susan Nyman Patricia Dejager Lowri 5450852 10.1080/02652030110098580 11962691 Determination of 1,3-dichloropropanol in soy sauces by automated headspace gas chromatography-mass spectrometry Food Additives and Contaminants 19 4 343–349 2002 Crews C Lebrun G Brereton P. A 28748623 10.1111/1541-4337.12120 3-Chloropropane-1,2-diol (3-MCPD) in Soy Sauce: A Review on the Formation, Reduction, and Detection of This Potential Carcinogen Comprehensive Reviews in Food Science and Food Safety 14 48–66 2015 Lee Bai Qin Khor Sook Mei 1 33401813 https://figshare.com/articles/journal_contribution/2063397/1/files/3666990.pdf See also 1,3-Difluoropropan-2-ol References Category:Secondary alcohols Category:Chlorohydrins Category:IARC Group 2B carcinogens