2-acylglycerophosphocholine O-acyltransferase

Class of enzymes 2-acylglycerophosphocholine O-acyltransferase 2.3.1.62 64295-73-4 0047190 In enzymology, a 2-acylglycerophosphocholine O-acyltransferase (2.3.1.62) is an enzyme that catalyzes the chemical reaction acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine CoA + phosphatidylcholine Thus, the two substrates of this enzyme are acyl-CoA and 2-acyl-sn-glycero-3-phosphocholine, whereas its two products are CoA and phosphatidylcholine. This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:2-acyl-sn-glycero-3-phosphocholine O-acyltransferase. Other names in common use include 2-acylglycerol-3-phosphorylcholine acyltransferase, and 2-acylglycerophosphocholine acyltransferase. This enzyme participates in glycerophospholipid metabolism. References 1 Lands WE, Hart P 1965 Metabolism of glycerolipids. VI. Specificities of acyl coenzyme A:phospholipid acyltransferases J. Biol. Chem. 240 5 1905–1911 10.1016/S0021-9258(18)97403-X free 14299609 Van Den Bosch H, Van Golde MG, Slotboom AJ, Van Deenen LL 1968 The acylation of isomeric monoacyl phosphatidylcholines Biochim. Biophys. Acta 152 694–703 5660084 4 10.1016/0005-2760(68)90115-x Biology no Category:EC 2.3.1 Category:Enzymes of unknown structure