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2-Aminothiazoline-4-carboxylic acid
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2-aminothiazoline-4-carboxylic.png 144px 2-Amino-4,5-dihydro-1,3-thiazole-4-carboxylic acid ACTA 2150-55-2 correct CAS correct FDA 48431VN59G 16526 15666 64777 218-433-0 1S/C4H6N2O2S/c5-4-6-2(1-9-4)3(7)8/h2H,1H2,(H2,5,6)(H,7,8) VHPXSBIFWDAFMB-UHFFFAOYSA-N C1C(N=C(S1)N)C(=O)O 4 6 2 2 1 White solid 212
2-Aminothiazoline-4-carboxylic acid (ACTA) is the organosulfur compound and a heterocycle with the formula HO2CCHCH2SCNH2N. This derivative of thiazoline is an intermediate in the industrial synthesis of L-cysteine, an amino acid. ACTA exists in equilibrium with its tautomer 2-iminothiazolidine-4-carboxylic acid.
It is produced by the reaction of methyl chloroacrylate with thiourea.Karlheinz Drauz Ian Grayson Axel Kleemann Hans-Peter Krimmer Wolfgang Leuchtenberger, Christoph Weckbecker 2006 10.1002/14356007.a02_057.pub2 It is also a biomarker for cyanide poisoning, as it results from the condensation of cysteine and cyanide.Determination of the cyanide metabolite 2-aminothiazoline-4-carboxylic acid in urine and plasma by gas chromatography-mass spectrometry Logue, Brian A. Kirschten, Nicholas P. Petrikovics, Ilona Moser, Matthew A. Rockwood, Gary A. Baskin, Steven I. Journal of Chromatography B 2005 819 2 237–244 10.1016/j.jchromb.2005.01.045 15833287 https://openprairie.sdstate.edu/chem_pubs/42 subscription
References
Category:Thiazolines
Category:Carboxylic acids